A new forward model for diffuse optical tomography

Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Diffuse Optical Spectroscopy and Imaging > Lunch Break and Poster Session - Monday

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Subjects: 

Biophotonics and Medical Engineering

Participants: 

Wenqi Lu 

(The Univ. of Birmingham)

Type:
Poster
Speech: English
In diffuse optical tomography (DOT), the diffusion equation (DE) is frequently used to model the light propagation in the medium. A general approach to solve the DE analytically is to apply the Green function but the solution only exists for homogeneous objects. For more complex DOT geometries, the finite element method (FEM) is normally employed to discretize the DE. However, FEM is limited in acquiring higher order accuracy when higher order basis (shape) functions are involved. Currently the differential operators in the DE are based on the classical local vector calculus. In this paper, by using the concepts of differential operators under the nonlocal vector calculus, we propose a nonlocal diffusion equation (NDE) as a new forward model to accurately describe light propagation in a turbid medium. A graph-based numerical method (GNM) is developed for the proposed NDE. We evaluate the proposed forward model on a semi-infinite homogeneous slab where the analytical solution exists. We perform a systematic comparison between the forward model based on GNM and the analytical solution. The comparison considers: i) the photon boundary flux at each detector; ii) the photon fluence rate at each vertex. Our experiments show that the results of the NDE (discretized by GNM) is quantitatively comparable to the analytical solution. The proposed forward model has an identical implementation for geometries in two and three dimensions due to the nature of the graph representation.

Author
Wenqi Lu, The Univ. of Birmingham Show Profile

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ICM -InternationalesCongressCenterMünchen
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EntranceEast
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Outdoor areas
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ConferenceCenter Nord
ICM
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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

Analysis of modern non-invasive methods of optoelectronic control of the skin

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

Clinical use of contrast agents to enhance skin structures in reflectance and fluorescence confocal microscopy and optical coherence tomography: a systematic review and patient cases

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

In vivo multimodal fibre-probe spectroscopy for glioblastoma detection in mouse model

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Diffuse Optical Spectroscopy and Imaging > Lunch Break and Poster Session - Monday

Spatial-frequency-domain optical tomography in the radiative transport regime

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Diffuse Optical Spectroscopy and Imaging > Lunch Break and Poster Session - Monday

Pathlength distribution of (sub)diffusively reflected light

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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