Pathlength distribution of (sub)diffusively reflected light

Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Diffuse Optical Spectroscopy and Imaging > Lunch Break and Poster Session - Monday

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Subjects: 

Biophotonics and Medical Engineering

Participants: 

Dirk Faber 

(Amsterdam UMC)

Type:
Poster
Speech: English
Knowledge of the path length distribution (PLD) of detected photons may be helpful in drafting models for sub-diffuse reflectance measurements such as Single Fiber Reflectance Spectroscopy, whereas moments of the pathlength distribution (mean and variance) may provide diagnostic information by themselves. The PLD of reflected photons can be determined from reflectance as a function of absorption coefficient through an inverse Laplace transform (iLT). Presence of noise hampers this approach. We evaluate Stehfest’s iLT method, using curve fitting as a noise reduction technique. We validate this approach in the diffuse regime using Monte Carlo simulations and analytical solutions for steady state and time-resolved reflectance. We show that the retrieved pathlength distributions from iLT correspond well with those obtained from the Monte Carlo simulations within the range of validity of the diffusion equations.

Author
Dirk Faber, Amsterdam UMC Show Profile

Location
Outdoor areas
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ConferenceCenter Nord
ICM -InternationalesCongressCenterMünchen
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EntranceWest
Atrium
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EntranceEast
EntranceNorth-West
EntranceNorth
Outdoor areas
EntranceNorth-East
ConferenceCenter Nord
ICM
B0
C1
C2
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C5
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B1
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EntranceWest
Atrium
EntranceEast
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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

Analysis of modern non-invasive methods of optoelectronic control of the skin

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

Clinical use of contrast agents to enhance skin structures in reflectance and fluorescence confocal microscopy and optical coherence tomography: a systematic review and patient cases

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

In vivo multimodal fibre-probe spectroscopy for glioblastoma detection in mouse model

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Diffuse Optical Spectroscopy and Imaging > Lunch Break and Poster Session - Monday

Spatial-frequency-domain optical tomography in the radiative transport regime

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Diffuse Optical Spectroscopy and Imaging > Lunch Break and Poster Session - Monday

Influence of optical path length on multi-wavelength measurement of oxy- and deoxy-hemoglobins in the skin

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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