Pathlength distribution of (sub)diffusively reflected light

Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Diffuse Optical Spectroscopy and Imaging > Lunch Break and Poster Session - Monday

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Subjects: 

Biophotonics and Medical Engineering

Participants: 

Dirk Faber 

(Amsterdam UMC)

Type:
Poster
Speech: English
Knowledge of the path length distribution (PLD) of detected photons may be helpful in drafting models for sub-diffuse reflectance measurements such as Single Fiber Reflectance Spectroscopy, whereas moments of the pathlength distribution (mean and variance) may provide diagnostic information by themselves. The PLD of reflected photons can be determined from reflectance as a function of absorption coefficient through an inverse Laplace transform (iLT). Presence of noise hampers this approach. We evaluate Stehfest’s iLT method, using curve fitting as a noise reduction technique. We validate this approach in the diffuse regime using Monte Carlo simulations and analytical solutions for steady state and time-resolved reflectance. We show that the retrieved pathlength distributions from iLT correspond well with those obtained from the Monte Carlo simulations within the range of validity of the diffusion equations.

Author
Dirk Faber, Amsterdam UMC Show Profile

Location
Outdoor areas
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EntranceNorth
ConferenceCenter Nord
ICM -InternationalesCongressCenterMünchen
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EntranceWest
Atrium
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EntranceEast
EntranceNorth-West
EntranceNorth
Outdoor areas
EntranceNorth-East
ConferenceCenter Nord
ICM
B0
C1
C2
C3
C4
C5
C6
B1
B2
B3
B4
B5
B6
EntranceWest
Atrium
EntranceEast
A1
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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

Blood plasma separation using microfluidic guiding channel in a continuous fashion

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

Monitoring x-rays exposed and unexposed cell culture media by means of surface-enhanced Raman spectroscopy

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

Terahertz time-domain spectroscopy for human gastric cancer diagnosis

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Preclinical and Clinical Optical Diagnostics > Lunch Break and Poster Session - Monday

Optical coherence tomography (OCT) imaging for detection of chronic lung allograft dysfunction (CLAD) in lung transplant patients

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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Jun
24
2019

European Conferences on Biomedical Optics (ECBO) > Diffuse Optical Spectroscopy and Imaging > Lunch Break and Poster Session - Monday

Monitoring radiofrequency ablation of biological tissue using broadband time-resolved diffuse optical spectroscopy

24. Jun 2019
12:45-14:15 h  |  Hall B0 Hall B0, ICM

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